6TMC
VIM-2_1dh-Triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-beta-lactamases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase class B VIM-2 | polymer | 266 | 28352.8 | 1 | UniProt (Q9K2N0) Pfam (PF00753) | Pseudomonas aeruginosa | BlaVIM-2,Class B carbapenemase VIM-2,Metallo beta-lactamase,Metallo-beta lactamase protein,Metallo-beta-lactamase VIM-2,VIM-2,VIM-2 beta-lactamase,VIM-2 class B metallo b-lactamase,VIM-2 type metallo-beta-lactamase |
| 2 | B (A) | 4-[2-(phenylsulfonyl)ethyl]-5-(propan-2-yloxymethyl)-1~{H}-1,2,3-triazole | non-polymer | 309.4 | 1 | Chemie (NL5) | |||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E (A) | HYDROXIDE ION | non-polymer | 17.0 | 1 | Chemie (OH) | |||
| 5 | F (A) | IODIDE ION | non-polymer | 126.9 | 1 | Chemie (IOD) | |||
| 6 | G (A) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28352.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 584.1 | |
| All* | Total formula weight | 28936.9 |
