6TMB
VIM-2_1di-Triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-beta-lactamases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase class B VIM-2 | polymer | 266 | 28352.8 | 2 | UniProt (Q9K2N0) Pfam (PF00753) | Pseudomonas aeruginosa | BlaVIM-2,Class B carbapenemase VIM-2,Metallo beta-lactamase,Metallo-beta lactamase protein,Metallo-beta-lactamase VIM-2,VIM-2,VIM-2 beta-lactamase,VIM-2 class B metallo b-lactamase,VIM-2 type metallo-beta-lactamase |
| 2 | C, D, E, J, K... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F, M (A, B) | HYDROXIDE ION | non-polymer | 17.0 | 2 | Chemie (OH) | |||
| 4 | G, H, N, O (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | I (B) | ~{N}-[[5-[[(phenylmethyl)amino]methyl]-1~{H}-1,2,3-triazol-4-yl]methyl]benzenesulfonamide | non-polymer | 357.4 | 1 | Chemie (9OB) | |||
| 6 | P (B) | IODIDE ION | non-polymer | 126.9 | 1 | Chemie (IOD) | |||
| 7 | Q, R (A, B) | water | water | 18.0 | 658 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56705.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1052.6 | |
| All* | Total formula weight | 57758.3 |
