6TM9
VIM-2_1cc-. Triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-beta-lactamases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase class B VIM-2 | polymer | 266 | 28352.8 | 1 | UniProt (Q9K2N0) Pfam (PF00753) | Pseudomonas aeruginosa | BlaVIM-2,Class B carbapenemase VIM-2,Metallo beta-lactamase,Metallo-beta lactamase protein,Metallo-beta-lactamase VIM-2,VIM-2,VIM-2 beta-lactamase,VIM-2 class B metallo b-lactamase,VIM-2 type metallo-beta-lactamase |
| 2 | B (A) | 2,5-bis(chloranyl)-~{N}-[[5-[(cyclohexylamino)methyl]-2~{H}-1,2,3-triazol-4-yl]methyl]benzenesulfonamide | non-polymer | 418.3 | 1 | Chemie (9NW) | |||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E (A) | HYDROXIDE ION | non-polymer | 17.0 | 1 | Chemie (OH) | |||
| 5 | F (A) | water | water | 18.0 | 353 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28352.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 566.2 | |
| All* | Total formula weight | 28919.0 |
