6TLE
Human Eg5 motor domain mutant E344K
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kinesin-like protein KIF11 | polymer | 367 | 40924.5 | 2 | UniProt (P52732) Pfam (PF00225) | Homo sapiens (Human) | Kinesin-like protein 1,Kinesin-like spindle protein HKSP,Kinesin-related motor protein Eg5,Thyroid receptor-interacting protein 5,TRIP-5 |
| 2 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, F (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | G (B) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 648 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 368 (UniProt: P52732)
| PDB | External Database | Details |
|---|---|---|
| Lys 344 | Glu 344 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81848.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 965.0 | |
| All* | Total formula weight | 82813.9 |
