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6TJK

Crystal Structure of Recombinant GBA in Complex with Bis-Tris Propane.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(AAA, BBB)
Lysosomal acid glucosylceramidasepolymer49755659.22UniProt (P04062)
Pfam (PF02055)
Pfam (PF17189)
Homo sapiens (human)Lysosomal acid GCase,Acid beta-glucosidase,Alglucerase,Beta-glucocerebrosidase,Beta-GC,Cholesterol glucosyltransferase,SGTase,Cholesteryl-beta-glucosidase,D-glucosyl-N-acylsphingosine glucohydrolase,Imiglucerase
2C, D
(A, B)
alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.72In PDB
GlyTouCan (G22573RC)
3CB, DB, E, EB, F...
(BBB, AAA)
SULFATE IONnon-polymer96.110Chemie (SO4)
4AA, G, HA
(AAA, BBB)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
5AB, BB, CA, DA, EA...
(BBB, AAA)
1,2-ETHANEDIOLnon-polymer62.143Chemie (EDO)
6BA, FB
(AAA, BBB)
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer282.32Chemie (B3P)
7KB, LB
(AAA, BBB)
waterwater18.0895Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111318.4
BranchedNumber of molecules2
Total formula weight1497.4
Non-Polymers*Number of molecules58
Total formula weight4857.8
All*Total formula weight117673.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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