6TIU
DROSOPHILA GTP-TUBULIN Y222F MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1 chain | polymer | 450 | 49989.3 | 2 | UniProt (P06603) Pfam (PF00091) Pfam (PF03953) | Drosophila melanogaster (Fruit fly) | |
| 2 | B, D (B, D) | Tubulin beta-1 chain | polymer | 447 | 50178.1 | 2 | UniProt (Q24560) Pfam (PF00091) Pfam (PF03953) | Drosophila melanogaster (Fruit fly) | Beta-1-tubulin |
| 3 | E (E) | Stathmin-4 | polymer | 143 | 16851.1 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (Rat) | Stathmin-like protein B3,RB3 |
| 4 | F, I, N, P (A, B, C, D) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | G, J, O, Q (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 6 | H, L, M, R, S (A, B, D) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 7 | K (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) |
Sequence modifications
A, C: 1 - 450 (UniProt: P06603)
B, D: 1 - 447 (UniProt: Q24560)
E: 4 - 145 (UniProt: P63043)
| PDB | External Database | Details |
|---|---|---|
| Arg 40 | Lys 40 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Phe 222 | Tyr 222 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Ala 4 | Ser 48 | engineered mutation |
| Ala 14 | Cys 58 | conflict |
| Trp 20 | Phe 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 217185.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3113.5 | |
| All* | Total formula weight | 220299.4 |
