6TGW
Crystal structure of human Aldehyde dehydrogenase 1A3 in complex with a selective inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Aldehyde dehydrogenase family 1 member A3 | polymer | 512 | 56177.3 | 4 | UniProt (P47895) Pfam (PF00171) | Homo sapiens (Human) | Aldehyde dehydrogenase 6,Retinaldehyde dehydrogenase 3,RalDH3 |
| 2 | E, H, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, G, J, L (A, B, C, D) | methyl 5-(1,3-benzodioxol-5-yl)-2-phenyl-pyrazolo[1,5-a]pyrimidine-7-carboxylate | non-polymer | 373.4 | 4 | Chemie (N98) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 224709.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4147.1 | |
| All* | Total formula weight | 228856.3 |
