6TDR
Crystal structure of the disulfide engineered HLA-A0201 molecule devoid of peptide (annealed)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | MHC class I antigen | polymer | 276 | 31925.4 | 2 | UniProt (F6IQS1) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B, D (B, D) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | E, F, G, J, K (A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | H, I, L (B, C, D) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 1142 | Chemie (HOH) |
Sequence modifications
A, C: 0 - 275 (UniProt: F6IQS1)
B, D: 2 - 100 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Cys 84 | Tyr 108 | conflict |
| Cys 139 | Ala 163 | conflict |
| Val 245 | Ala 269 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 87609.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 379.3 | |
| All* | Total formula weight | 87988.7 |
