6TDA
Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.2 | polymer | 135 | 15303.9 | 2 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 2 | B, F (B, F) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 3 | C, G (C, G) | Histone H2A | polymer | 129 | 13978.2 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) | Xenopus laevis (African clawed frog) | |
| 4 | D, H (D, H) | Histone H2B 1.1 | polymer | 122 | 13524.8 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 5 | I (I) | DNA-I | polymer | 237 | 72876.3 | 1 | synthetic construct | ||
| 6 | J (J) | DNA-J | polymer | 237 | 73478.9 | 1 | synthetic construct | ||
| 7 | K (K) | Chromatin structure-remodeling complex subunit SFH1 | polymer | 426 | 48833.2 | 1 | UniProt (Q06168) Pfam (PF04855) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | RSC complex subunit SFH1,SNF5 homolog 1 |
| 8 | L (L) | Chromatin structure-remodeling complex protein RSC8 | polymer | 1114 | 126489.9 | 1 | UniProt (P43609) Pfam (PF16495) Pfam (PF04433) Pfam (PF00569) Pfam (PF00249) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Remodel the structure of chromatin complex subunit 8,SWI3 homolog |
| 9 | M (M) | Chromatin structure-remodeling complex subunit RSC7 | polymer | 435 | 49716.5 | 1 | UniProt (P32832) Pfam (PF08624) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Nuclear protein localization protein 6,Remodel the structure of chromatin complex subunit 7 |
| 10 | N (N) | Chromatin structure-remodeling complex subunit RSC9 | polymer | 581 | 65289.3 | 1 | UniProt (Q03124) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | RSC complex subunit RSC9,Remodel the structure of chromatin complex subunit 9 |
| 11 | O (O) | Chromatin structure-remodeling complex protein RSC6 | polymer | 483 | 54222.7 | 1 | UniProt (P25632) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Remodel the structure of chromatin complex subunit 6 |
| 12 | P (P) | Chromatin structure-remodeling complex protein RSC58 | polymer | 502 | 57871.3 | 1 | UniProt (Q07979) Pfam (PF00439) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Remodel the structure of chromatin complex subunit 58 |
| 13 | Q (Q) | High temperature lethal protein 1 | polymer | 78 | 9192.5 | 1 | UniProt (Q9URQ5) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Chromatin structure-remodeling complex protein HTL1 |
| 14 | R (R) | Chromatin structure-remodeling complex subunit RSC4 | polymer | 625 | 72372.4 | 1 | UniProt (Q02206) Pfam (PF00439) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | RSC complex subunit RSC4,Remodel the structure of chromatin complex subunit 4 |
| 15 | S (S) | Nuclear protein STH1/NPS1 | polymer | 1359 | 156982.4 | 1 | UniProt (P32597) Pfam (PF07529) Pfam (PF00176) Pfam (PF00271) Pfam (PF14619) Pfam (PF00439) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | ATP-dependent helicase STH1,Chromatin structure-remodeling complex protein STH1,SNF2 homolog |
| 16 | T (T) | Actin-related protein 7 | polymer | 477 | 54613.3 | 1 | UniProt (Q12406) Pfam (PF00022) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Actin-like protein ARP7,Chromatin structure-remodeling complex protein ARP7,SWI/SNF complex component ARP7 |
| 17 | U (U) | Actin-like protein ARP9 | polymer | 467 | 53366.4 | 1 | UniProt (Q05123) Pfam (PF00022) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Chromatin structure-remodeling complex protein ARP9,SWI/SNF complex component ARP9 |
| 18 | V (V) | Regulator of Ty1 transposition protein 102 | polymer | 157 | 18005.2 | 1 | UniProt (P53330) Pfam (PF09510) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | |
| 19 | W (X) | Unknown protein | polymer | 383 | 32613.1 | 1 | Saccharomyces cerevisiae S288C | ||
| 20 | X (L) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A, E: 1 - 135 (UniProt: P84233)
D, H: 1 - 122 (UniProt: P02281)
T: 2 - 477 (UniProt: Q12406)
U: 2 - 467 (UniProt: Q05123)
V: 2 - 157 (UniProt: P53330)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Gly 103 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Thr 29 | Ser 33 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 23 |
| Total formula weight | 1054063.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 1054129.1 |
