6TCJ
Crystal structure of the BCL6 BTB domain in complex with a hybrid BTB-binding (HBP) peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | B-cell lymphoma 6 protein | polymer | 126 | 14498.8 | 2 | UniProt (P41182) Pfam (PF00651) | Homo sapiens (Human) | BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51 |
| 2 | C, D (C, D) | Hybrid BTB-binding (HBP) peptide | polymer | 17 | 1943.2 | 2 | synthetic construct | ||
| 3 | E (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A, B: 6 - 129 (UniProt: P41182)
| PDB | External Database | Details |
|---|---|---|
| Gly 4 | - | expression tag |
| Pro 5 | - | expression tag |
| Gln 8 | Cys 8 | engineered mutation |
| Arg 67 | Cys 67 | engineered mutation |
| Asn 84 | Cys 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 32884.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 32907.0 |
