6TBZ
Crystal structure of the MH1 domain of Smad5-Smad3 chimera construct bound to the GGCGC site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mothers against decapentaplegic homolog 5 | polymer | 131 | 15032.5 | 1 | UniProt (Q99717) Pfam (PF03165) UniProt (by SIFTS) (Q56I99) In PDB | Homo sapiens (Human) | Mothers against DPP homolog 5,JV5-1,SMAD family member 5,hSmad5 |
| 2 | B, C | DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP*GP*CP*A)-3') | polymer | 16 | 4900.2 | 2 | Homo sapiens | ||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence modifications
A: 8 - 138 (UniProt: Q99717)
| PDB | External Database | Details |
|---|---|---|
| Glu 22 | - | insertion |
| Gln 23 | - | insertion |
| Asn 24 | - | insertion |
| Gly 25 | Asp 25 | conflict |
| Gln 26 | Glu 26 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 24832.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 24898.3 |
