6TB2
Structure of human haptoglobin-hemoglobin bound to S. aureus IsdH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 1 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (Human) | Alpha-globin,Hemoglobin alpha chain |
| 2 | B (B) | Hemoglobin subunit beta | polymer | 146 | 15890.2 | 1 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (Human) | Beta-globin,Hemoglobin beta chain |
| 3 | C (C) | Haptoglobin | polymer | 267 | 29787.9 | 1 | UniProt (P00738) Pfam (PF00089) | Homo sapiens (Human) | Zonulin |
| 4 | D, E (D, E) | Cell wall surface anchor family protein | polymer | 354 | 40971.7 | 2 | UniProt (A0A0E8IWL6) Pfam (PF05031) Pfam (PF20861) UniProt (by SIFTS) (Q2FXJ2) | Staphylococcus aureus | Haptoglobin-binding heme uptake protein HarA,Heme transporter HarA |
| 5 | F, G (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) |
Sequence modifications
C: 148 - 406 (UniProt: P00738)
D, E: 321 - 655 (UniProt: A0A0E8IWL6)
| PDB | External Database | Details |
|---|---|---|
| His 140 | - | expression tag |
| His 141 | - | expression tag |
| His 142 | - | expression tag |
| His 143 | - | expression tag |
| His 144 | - | expression tag |
| His 145 | - | expression tag |
| His 146 | - | expression tag |
| His 147 | - | expression tag |
| Ser 184 | Asn 184 | conflict |
| Ser 207 | Asn 207 | conflict |
| Ser 211 | Asn 211 | conflict |
| Ser 241 | Asn 241 | conflict |
| PDB | External Database | Details |
|---|---|---|
| His 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
| Ser 308 | - | expression tag |
| Ser 309 | - | expression tag |
| Gly 310 | - | expression tag |
| Leu 311 | - | expression tag |
| Val 312 | - | expression tag |
| Pro 313 | - | expression tag |
| Arg 314 | - | expression tag |
| Gly 315 | - | expression tag |
| Ser 316 | - | expression tag |
| His 317 | - | expression tag |
| Met 318 | - | expression tag |
| Leu 319 | - | expression tag |
| Glu 320 | - | expression tag |
| Ala 642 | Tyr 642 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 142771.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1233.0 | |
| All* | Total formula weight | 144004.9 |
