6T9X

Crystal structure of formate dehydrogenase FDH2 D222Q/Q223R mutant enzyme from Granulicella mallensis MP5ACTX8 in complex with NADP and Azide.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C, D	Formate dehydrogenase	polymer	386	42631.7	4	UniProt (G8NTI5) Pfam (PF00389) Pfam (PF02826) In PDB	Granulicella mallensis MP5ACTX8	FDH,NAD-dependent formate dehydrogenase
2	B, A, C, D	AZIDE ION	non-polymer		42.0	4	Chemie (AZI)
3	B, A, C, D	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
4		water	water		18.0	745	Chemie (HOH)

Sequence modifications

B, A, C, D: 1 - 386 (UniProt: G8NTI5)

PDB	External Database	Details
Gln 222	Asp 222	engineered mutation
Arg 223	Gln 223	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	170526.7
Non-Polymers*	Number of molecules	8
	Total formula weight	3141.7
All*	Total formula weight	173668.4

*Water molecules are not included.