6T9U
Bovine Trypsine in complex with the synthetic inhibitor (S)-3'-(N-(1-(4-(3-(tert-butyl)ureido)piperidin-1-yl)-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl)sulfamoyl)-[1,1'-biphenyl]-3-carboximidamide (MI-490)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cationic Trypsin | polymer | 246 | 25806.2 | 1 | UniProt (P00760) Pfam (PF00089) | Bos taurus | |
| 2 | B, D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 3 | C (A) | 1-~{tert}-butyl-3-[1-[(2~{S})-3-(3-carbamimidoylphenyl)-2-[[3-(3-carbamimidoylphenyl)phenyl]sulfonylamino]propanoyl]piperidin-4-yl]urea | non-polymer | 646.8 | 1 | Chemie (MZE) | |||
| 4 | E (A) | trifluoroacetic acid | non-polymer | 114.0 | 1 | Chemie (TFA) | |||
| 5 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | G (A) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25806.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 957.2 | |
| All* | Total formula weight | 26763.4 |
