6T9D
Crystal structure of a bispecific DutaFab in complex with human VEGF121
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (AAA, HHH) | VP mat DutaFab VH chain | polymer | 220 | 23502.2 | 2 | Homo sapiens (Human) | ||
| 2 | B, F (BBB, LLL) | VP mat DutaFab VL chain | polymer | 213 | 23820.4 | 2 | Homo sapiens (Human) | ||
| 3 | C, D (CCC, DDD) | Vascular endothelial growth factor A | polymer | 121 | 14078.1 | 2 | UniProt (P15692) Pfam (PF00341) | Homo sapiens (Human) | VEGF-A,Vascular permeability factor,VPF |
| 4 | G, H, I, J, K... (AAA, BBB, CCC, DDD, HHH...) | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
CCC, DDD: 1 - 121 (UniProt: P15692)
| PDB | External Database | Details |
|---|---|---|
| Asn 115 | Lys 141 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 122801.4 | |
| All* | Total formula weight | 122801.4 |
