6T5P
Human Carbonic anhydrase XII bound by 3,5-Di-tert-butylbenzenesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 12 | polymer | 263 | 29917.3 | 4 | UniProt (O43570) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase XII,Carbonic anhydrase XII,CA-XII,Tumor antigen HOM-RCC-3.1.3 |
| 2 | E, G, J, O (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, H, K, P (A, B, C, D) | 3,5-di~{tert}-butylbenzenesulfonamide | non-polymer | 269.4 | 4 | Chemie (VD8) | |||
| 4 | I, L, M, N, Q... (B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 915 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 263 (UniProt: O43570)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119669.3 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1711.7 | |
| All* | Total formula weight | 121380.9 |
