6T59
Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A3) | Ribosomal protein L8 | polymer | 257 | 28088.9 | 1 | UniProt (G1TT27) Pfam (PF00181) Pfam (PF03947) | Oryctolagus cuniculus (Rabbit) | |
| 2 | B (B3) | uL3 | polymer | 403 | 46108.0 | 1 | UniProt (G1TL06) Pfam (PF00297) | Oryctolagus cuniculus (Rabbit) | |
| 3 | C (C3) | uL4 | polymer | 425 | 47727.6 | 1 | Oryctolagus cuniculus | ||
| 4 | D (D3) | 60S ribosomal protein L5 | polymer | 297 | 34481.8 | 1 | UniProt (G1SYJ6) UniProt (by SIFTS) (P19949) | Oryctolagus cuniculus (Rabbit) | |
| 5 | E (E3) | 60S ribosomal protein L6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) | Oryctolagus cuniculus (Rabbit) | |
| 6 | F (F3) | Ul30 | polymer | 247 | 29201.8 | 1 | UniProt (G1TUB1) Pfam (PF08079) Pfam (PF00327) | Oryctolagus cuniculus (Rabbit) | |
| 7 | G (G3) | eL8 | polymer | 319 | 36221.5 | 1 | Oryctolagus cuniculus | ||
| 8 | H (H3) | uL6 | polymer | 192 | 21871.4 | 1 | UniProt (G1TX33) Pfam (PF00347) UniProt (by SIFTS) (G1SWI6) | Oryctolagus cuniculus (Rabbit) | |
| 9 | I (I3) | 60S ribosomal protein L10 | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L10 (Predicted) |
| 10 | J (J3) | Ribosomal protein L11 | polymer | 178 | 20288.5 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) | Oryctolagus cuniculus (Rabbit) | |
| 11 | K (L3) | eL13 | polymer | 211 | 24331.7 | 1 | Oryctolagus cuniculus | ||
| 12 | L (M3) | Ribosomal protein L14 | polymer | 218 | 23870.5 | 1 | UniProt (G1SZ12) Pfam (PF01929) | Oryctolagus cuniculus (Rabbit) | |
| 13 | M (N3) | Ribosomal protein L15 | polymer | 204 | 24207.3 | 1 | UniProt (G1T0C1) Pfam (PF00827) | Oryctolagus cuniculus (Rabbit) | |
| 14 | N (O3) | uL13 | polymer | 203 | 23533.3 | 1 | Oryctolagus cuniculus | ||
| 15 | O (P3) | uL22 | polymer | 184 | 21444.2 | 1 | UniProt (G1TVT6) Pfam (PF00237) UniProt (by SIFTS) (G1SCJ6) | Oryctolagus cuniculus (Rabbit) | |
| 16 | P (Q3) | eL18 | polymer | 188 | 21653.6 | 1 | Oryctolagus cuniculus | ||
| 17 | Q (R3) | eL19 | polymer | 196 | 23535.3 | 1 | Oryctolagus cuniculus | ||
| 18 | R (S3) | eL20 | polymer | 176 | 20827.6 | 1 | Oryctolagus cuniculus | ||
| 19 | S (T3) | eL21 | polymer | 160 | 18610.0 | 1 | UniProt (G1SHQ2) Pfam (PF01157) | Oryctolagus cuniculus (Rabbit) | |
| 20 | T (U3) | eL22 | polymer | 128 | 14813.0 | 1 | Oryctolagus cuniculus | ||
| 21 | U (V3) | Ribosomal protein L23 | polymer | 140 | 14892.5 | 1 | UniProt (G1T6D1) Pfam (PF00238) | Oryctolagus cuniculus (Rabbit) | |
| 22 | V (W3) | eL24 | polymer | 157 | 17825.1 | 1 | UniProt (G1SE28) Pfam (PF01246) | Oryctolagus cuniculus (Rabbit) | |
| 23 | W (X3) | uL23 | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) | Oryctolagus cuniculus (Rabbit) | |
| 24 | X (Y3) | Ribosomal protein L26 | polymer | 145 | 17303.4 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) | Oryctolagus cuniculus (Rabbit) | |
| 25 | Y (Z3) | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) | Oryctolagus cuniculus (Rabbit) | |
| 26 | Z (a3) | uL15 | polymer | 148 | 16620.6 | 1 | UniProt (G1SNY0) Pfam (PF00828) | Oryctolagus cuniculus (Rabbit) | |
| 27 | AA (b3) | eL29 | polymer | 226 | 24931.6 | 1 | UniProt (G1SGR6) Pfam (PF01779) | Oryctolagus cuniculus (Rabbit) | |
| 28 | BA (c3) | eL30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) | Oryctolagus cuniculus (Rabbit) | |
| 29 | CA (d3) | eL31 | polymer | 125 | 14494.9 | 1 | UniProt (G1SHG0) Pfam (PF01198) | Oryctolagus cuniculus (Rabbit) | |
| 30 | DA (e3) | eL32 | polymer | 135 | 15898.9 | 1 | UniProt (G1U437) Pfam (PF01655) UniProt (by SIFTS) (G1TUN8) | Oryctolagus cuniculus (Rabbit) | |
| 31 | EA (f3) | eL33 | polymer | 110 | 12580.8 | 1 | UniProt (G1SF08) Pfam (PF01247) | Oryctolagus cuniculus (Rabbit) | |
| 32 | FA (g3) | eL34 | polymer | 116 | 13196.9 | 1 | UniProt (G1U945) Pfam (PF01199) UniProt (by SIFTS) (G1TXG5) | Oryctolagus cuniculus (Rabbit) | |
| 33 | GA (h3) | uL29 | polymer | 123 | 14566.6 | 1 | UniProt (G1SIT5) Pfam (PF00831) | Oryctolagus cuniculus (Rabbit) | |
| 34 | HA (i3) | 60S ribosomal protein L36 | polymer | 105 | 12263.8 | 1 | UniProt (G1TTQ5) Pfam (PF01158) | Oryctolagus cuniculus (Rabbit) | |
| 35 | IA (j3) | Ribosomal protein L37 | polymer | 97 | 11111.0 | 1 | UniProt (U3KPD5) Pfam (PF01907) | Oryctolagus cuniculus (Rabbit) | |
| 36 | JA (k3) | eL38 | polymer | 70 | 8238.9 | 1 | UniProt (G1U001) Pfam (PF01781) | Oryctolagus cuniculus (Rabbit) | |
| 37 | KA (l3) | eL39 | polymer | 51 | 6455.8 | 1 | UniProt (G1TTN1) Pfam (PF00832) | Oryctolagus cuniculus (Rabbit) | |
| 38 | LA (m3) | eL40 | polymer | 102 | 11699.8 | 1 | Oryctolagus cuniculus | ||
| 39 | MA (n3) | 60s ribosomal protein l41 | polymer | 25 | 3473.5 | 1 | UniProt (A0A087WNH4) Pfam (PF05162) | Oryctolagus cuniculus (Rabbit) | eL41 |
| 40 | NA (o3) | eL42 | polymer | 106 | 12477.0 | 1 | UniProt (G1U344) Pfam (PF00935) UniProt (by SIFTS) (G1T040) | Oryctolagus cuniculus (Rabbit) | |
| 41 | OA (p3) | eL43 | polymer | 92 | 10299.4 | 1 | UniProt (G1SY53) Pfam (PF01780) | Oryctolagus cuniculus (Rabbit) | |
| 42 | PA (r3) | eL28 | polymer | 137 | 15783.6 | 1 | UniProt (G1U7L1) Pfam (PF01778) | Oryctolagus cuniculus (Rabbit) | |
| 43 | QA (s3) | uL10 | polymer | 318 | 34380.5 | 1 | Oryctolagus cuniculus | ||
| 44 | RA (t3) | Ribosomal protein L12 | polymer | 165 | 17847.6 | 1 | UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298) | Oryctolagus cuniculus (Rabbit) | |
| 45 | SA (23) | P-site tRNA | polymer | 76 | 24436.6 | 1 | Oryctolagus cuniculus | ||
| 46 | TA (54) | 28S ribosomal RNA | polymer | 3543 | 1148115.4 | 1 | Oryctolagus cuniculus | ||
| 47 | UA (74) | 5S ribosomal RNA | polymer | 120 | 38691.9 | 1 | Oryctolagus cuniculus | ||
| 48 | VA (84) | 5.8S ribosomal RNA | polymer | 156 | 50143.6 | 1 | Oryctolagus cuniculus | ||
| 49 | WA (NI) | Nascent polypeptide-associated complex subunit alpha N-terminal region | polymer | 29 | 2147.4 | 1 | Oryctolagus cuniculus | ||
| 50 | XA (NA) | Nascent polypeptide-associated complex subunit alpha | polymer | 215 | 23406.8 | 1 | Oryctolagus cuniculus | ||
| 51 | YA (NB) | Transcription factor BTF3 | polymer | 206 | 22170.0 | 1 | Oryctolagus cuniculus | ||
| 52 | ZA (TT) | Tetratricopeptide repeat protein 5 | polymer | 440 | 48988.4 | 1 | UniProt (Q8N0Z6) Pfam (PF16669) | Homo sapiens (Human) | TPR repeat protein 5,Stress-responsive activator of p300,Strap |
| 53 | AB (1) | Tubulin Beta | polymer | 64 | 7164.0 | 1 | Oryctolagus cuniculus | ||
| 54 | AC, AD, AE, AF, AG... (54, P3, V3, a3, 74...) | MAGNESIUM ION | non-polymer | 24.3 | 220 | Chemie (MG) | |||
| 55 | FB, HB, JB, KB, LB (g3, j3, m3, o3, p3) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) |
Sequence modifications
B3: 2 - 403 (UniProt: G1TL06)
D3: 2 - 297 (UniProt: G1SYJ6)
F3: 1 - 247 (UniProt: G1TUB1)
a3: 2 - 148 (UniProt: G1SNY0)
k3: 1 - 70 (UniProt: G1U001)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Arg 61 | Gly 61 | conflict |
| Arg 93 | Gly 93 | conflict |
| Met 131 | Val 131 | conflict |
| Ile 153 | Val 153 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Lys 24 | Asn 24 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 53 |
| Total formula weight | 2256504.8 | |
| Non-Polymers* | Number of molecules | 225 |
| Total formula weight | 5674.1 | |
| All* | Total formula weight | 2262179.0 |
