6T3Y

Improved High Resolution Structure of MHC Class II complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MHC class II alpha chain	polymer	183	21033.5	1	UniProt (Q4U5Z6) Pfam (PF00993) Pfam (PF07654)	Gallus gallus (Chicken)	MHC class II antigen alpha chain
2	B (B)	MHC class II beta chain 2	polymer	224	24879.6	1	UniProt (B5BSA0) Pfam (PF00969) Pfam (PF07654)	Gallus gallus (Chicken)
3	C, E, F (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	D (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
5	G, H (A, B)	water	water		18.0	317	Chemie (HOH)

Sequence modifications

A: 6 - 186 (UniProt: Q4U5Z6)

PDB	External Database	Details
Ala 4	-	expression tag
Arg 5	-	expression tag

B: 39 - 224 (UniProt: B5BSA0)

PDB	External Database	Details
Ala 1	-	expression tag
Asp 2	-	expression tag
Arg 3	-	expression tag
Pro 4	-	expression tag
Gln 5	-	expression tag
Ile 6	-	expression tag
Glu 7	-	expression tag
Ser 8	-	expression tag
Leu 9	-	expression tag
Ser 10	-	expression tag
Leu 11	-	expression tag
Asn 12	-	expression tag
Gly 13	-	expression tag
Val 14	-	expression tag
Pro 15	-	expression tag
Asn 16	-	expression tag
Ile 17	-	expression tag
Phe 18	-	expression tag
Leu 19	-	expression tag
Ser 20	-	expression tag
Thr 21	-	expression tag
Lys 22	-	expression tag
Ala 23	-	expression tag
Gly 24	-	expression tag
Gly 25	-	expression tag
Gly 26	-	expression tag
Gly 27	-	expression tag
Ser 28	-	expression tag
Gly 29	-	expression tag
Gly 30	-	expression tag
Gly 31	-	expression tag
Gly 32	-	expression tag
Ser 33	-	expression tag
Gly 34	-	expression tag
Gly 35	-	expression tag
Gly 36	-	expression tag
Gly 37	-	expression tag
Ser 38	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45913.2
Non-Polymers*	Number of molecules	4
	Total formula weight	335.3
All*	Total formula weight	46248.5

*Water molecules are not included.