6T3J
Dual Epitope Targeting by Anti-DR5 Antibodies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, F) | IgG1-hDR5-01-Heavy Chain | polymer | 232 | 25099.0 | 2 | Homo sapiens (Human) | ||
| 2 | B, G (B, G) | IgG1-hDR5-01-Light Chain | polymer | 214 | 23436.0 | 2 | Homo sapiens (Human) | ||
| 3 | C, H (C, H) | IgG1-hDR5-05-Heavy Chain | polymer | 232 | 25108.1 | 2 | Homo sapiens (Human) | ||
| 4 | D, I (D, I) | IgG1-hDR5-05-Light Chain | polymer | 213 | 23385.7 | 2 | Homo sapiens (Human) | ||
| 5 | E, J (E, J) | Tumor necrosis factor receptor superfamily member 10B | polymer | 131 | 14663.3 | 2 | UniProt (O14763) Pfam (PF00020) | Homo sapiens (Human) | Death receptor 5,TNF-related apoptosis-inducing ligand receptor 2,TRAIL-R2 |
Sequence modifications
E, J: 58 - 184 (UniProt: O14763)
| PDB | External Database | Details |
|---|---|---|
| Glu 185 | - | expression tag |
| Pro 186 | - | expression tag |
| Glu 187 | - | expression tag |
| Ala 188 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 223384.3 | |
| All* | Total formula weight | 223384.3 |
