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6T23

Cryo-EM structure of jasplakinolide-stabilized F-actin (aged)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Actin, alpha skeletal musclepolymer37541875.65UniProt (P68135)
Pfam (PF00022)
Oryctolagus cuniculus (Rabbit)Alpha-actin-1
2F, K, O, S, W
(A, B, C, D, E)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.25Chemie (ADP)
3G, L, P, T, X
(A, B, C, D, E)
PHOSPHATE IONnon-polymer95.05Chemie (PO4)
4H, M, Q, U, Y
(A, B, C, D, E)
MAGNESIUM IONnon-polymer24.35Chemie (MG)
5I, J, N, R, V
(A, B, C, D, E)
(4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetronenon-polymer673.85Chemie (9ZK)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight209378.2
Non-Polymers*Number of molecules20
Total formula weight6101.6
All*Total formula weight215479.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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