6T1N
Crystal structure of MLLT1 (ENL) YEATS domain in complexed with benzimidazole-amide derivative 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein ENL | polymer | 154 | 18225.0 | 1 | UniProt (Q03111) Pfam (PF03366) | Homo sapiens (Human) | YEATS domain-containing protein 1 |
| 2 | B (A) | 4-chloranyl-~{N}-[2-(piperidin-1-ylmethyl)-3~{H}-benzimidazol-5-yl]benzamide | non-polymer | 368.9 | 1 | Chemie (M7Z) | |||
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | J (A) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 1 - 148 (UniProt: Q03111)
| PDB | External Database | Details |
|---|---|---|
| His 149 | - | expression tag |
| His 150 | - | expression tag |
| His 151 | - | expression tag |
| His 152 | - | expression tag |
| His 153 | - | expression tag |
| His 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18225.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 803.3 | |
| All* | Total formula weight | 19028.3 |
