6T1L

Crystal structure of MLLT1 (ENL) YEATS domain in complexed with piperazine-urea derivative 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein ENL	polymer	154	18225.0	1	UniProt (Q03111) Pfam (PF03366) In PDB	Homo sapiens (Human)	YEATS domain-containing protein 1
2	A	1,2-ETHANEDIOL	non-polymer		62.1	10	Chemie (EDO)
3	A	~{N}-[[4-(diethylaminomethyl)phenyl]methyl]-4-pyrimidin-2-yl-piperazine-1-carboxamide	non-polymer		382.5	1	Chemie (M7N)
4		water	water		18.0	41	Chemie (HOH)

Sequence modifications

A: 1 - 148 (UniProt: Q03111)

PDB	External Database	Details
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	18225.0
Non-Polymers*	Number of molecules	11
	Total formula weight	1003.2
All*	Total formula weight	19228.2

*Water molecules are not included.