6SX2

dsRNA recognition by R38AK41A mutant of H7N1 NS1 RNA Binding Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Non-structural protein 1	polymer	77	8672.9	2	UniProt (Q1PST0)	Influenza A virus (A/turkey/Italy/977/1999(H7N1))	NS1
2	C, D (C, D)	RNA (5'-R(*GP*GP*UP*AP*AP*CP*UP*GP*UP*UP*AP*CP*AP*GP*UP*UP*AP*CP*C)-3')	polymer	19	6039.6	2		synthetic construct
3	E, F, G, H, I... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	9	Chemie (EDO)
4	N, O, P, Q (A, B, C, D)	water	water		18.0	158	Chemie (HOH)

Sequence modifications

A, B: 2 - 73 (UniProt: Q1PST0)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Ser 1	-	expression tag
Ala 38	Arg 38	engineered mutation
Ala 41	Lys 41	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	29425.1
Non-Polymers*	Number of molecules	9
	Total formula weight	558.6
All*	Total formula weight	29983.7

*Water molecules are not included.