6SWO

C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH iBET-BD1 (GSK778)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (AAA)	Bromodomain-containing protein 2	polymer	115	13432.5	1	UniProt (P25440) Pfam (PF00439)	Homo sapiens (Human)	O27.1.1,Really interesting new gene 3 protein
2	B (AAA)	4-[2-(methoxymethyl)-1-[(1~{R})-1-phenylethyl]-8-[[(3~{S})-pyrrolidin-3-yl]methoxy]imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole	non-polymer		511.6	1	Chemie (LWB)
3	C, D (AAA)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	E (AAA)	water	water		18.0	172	Chemie (HOH)

Sequence modifications

AAA: 344 - 455 (UniProt: P25440)

PDB	External Database	Details
Gly 341	-	expression tag
Ser 342	-	expression tag
Met 343	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	13432.5
Non-Polymers*	Number of molecules	3
	Total formula weight	635.8
All*	Total formula weight	14068.2

*Water molecules are not included.