6SWO
C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH iBET-BD1 (GSK778)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | AAA | Bromodomain-containing protein 2 | polymer | 115 | 13432.5 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | AAA | 4-[2-(methoxymethyl)-1-[(1~{R})-1-phenylethyl]-8-[[(3~{S})-pyrrolidin-3-yl]methoxy]imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole | non-polymer | 511.6 | 1 | Chemie (LWB) | |||
| 3 | AAA | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence modifications
AAA: 344 - 455 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Gly 341 | - | expression tag |
| Ser 342 | - | expression tag |
| Met 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13432.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 635.8 | |
| All* | Total formula weight | 14068.2 |
