6SUK
Crystal structure of Neprilysin in complex with Omapatrilat.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neprilysin | polymer | 699 | 79918.9 | 1 | UniProt (P08473) Pfam (PF05649) Pfam (PF01431) | Homo sapiens (Human) | Atriopeptidase,Common acute lymphocytic leukemia antigen,CALLA,Enkephalinase,Neutral endopeptidase 24.11,Neutral endopeptidase,Skin fibroblast elastase,SFE |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, E, F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | G (A) | Omapatrilat | non-polymer | 408.5 | 1 | Chemie (FT8) | |||
| 5 | H, L (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | I, J, K, M (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | N (A) | water | water | 18.0 | 553 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 79918.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1819.3 | |
| All* | Total formula weight | 81738.1 |
