6SQU
Crystal structure of human SHIP2 catalytic domain in complex with 1,2,4 Dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | polymer | 316 | 36243.9 | 2 | UniProt (O15357) In PDB | Homo sapiens (Human) | Inositol polyphosphate phosphatase-like protein 1,INPPL-1,Protein 51C,SH2 domain-containing inositol 5'-phosphatase 2,SHIP-2 |
| 2 | B | 5,5'-(ethane-1,2-diylbis(oxy))bis(benzene-5,4,2,1,-tetrayl)hexakisphosphate | non-polymer | 790.1 | 1 | Chemie (D7I) | |||
| 3 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A, B: 419 - 732 (UniProt: O15357)
| PDB | External Database | Details |
|---|---|---|
| Ser 417 | - | expression tag |
| Met 418 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72487.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 790.1 | |
| All* | Total formula weight | 73277.8 |
