6SPM
Crystal structure of cAMP-dependent protein kinase A (CHO PKA) in complex with 4-(trifluoromethyl)benzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41113.8 | 1 | UniProt (P25321) Pfam (PF00069) | Cricetulus griseus (Chinese hamster) | PKA C-alpha |
| 2 | B (A) | 4-(trifluoromethyl)benzoic acid | non-polymer | 190.1 | 1 | Chemie (3AE) | |||
| 3 | C (A) | METHANOL | non-polymer | 32.0 | 1 | Chemie (MOH) | |||
| 4 | D, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | F (A) | water | water | 18.0 | 306 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P25321)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41113.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 378.4 | |
| All* | Total formula weight | 41492.2 |
