6SOI

Fragment N13788a in complex with MAP kinase p38-alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mitogen-activated protein kinase 14	polymer	380	43721.7	1	UniProt (P47811) Pfam (PF00069) In PDB	Mus musculus (House mouse)	MAPK 14,CRK1,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha
2	A	methyl ~{N}-[3-(methoxycarbonylamino)phenyl]carbamate	non-polymer		224.2	1	Chemie (LOK)
3	A	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
4	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	A	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)
7		water	water		18.0	259	Chemie (HOH)

Sequence modifications

A: 1 - 359 (UniProt: P47811)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Gln -9	-	expression tag
Asp -8	-	expression tag
Pro -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43721.7
Non-Polymers*	Number of molecules	10
	Total formula weight	696.0
All*	Total formula weight	44417.7

*Water molecules are not included.