6SO4

Fragment RZ132 in complex with MAP kinase p38-alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Mitogen-activated protein kinase 14	polymer	381	43808.7	1	UniProt (P47811) Pfam (PF00069)	Mus musculus (House mouse)	MAPK 14,CRK1,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha
2	B (A)	(2~{S})-2-methyl-4-(oxetan-3-yl)-~{N}-(phenylmethyl)piperazine-2-carboxamide	non-polymer		289.4	1	Chemie (LO8)
3	C, D, E, F, G... (A)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
4	I (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	J, K (A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	L (A)	water	water		18.0	278	Chemie (HOH)

Sequence modifications

A: 1 - 360 (UniProt: P47811)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Gln -9	-	expression tag
Asp -8	-	expression tag
Pro -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43808.7
Non-Polymers*	Number of molecules	10
	Total formula weight	718.5
All*	Total formula weight	44527.3

*Water molecules are not included.