6SMB
Human jak1 kinase domain in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein kinase JAK1 | polymer | 301 | 34689.5 | 2 | UniProt (P23458) Pfam (PF07714) | Homo sapiens (Human) | Janus kinase 1,JAK-1 |
| 2 | C, D (A, B) | ~{N}-[3-[2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]-5-methyl-pyrimidin-4-yl]-1~{H}-indol-7-yl]-2-methyl-pyridine-3-carboxamide | non-polymer | 468.5 | 2 | Chemie (LKQ) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69379.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 937.0 | |
| All* | Total formula weight | 70316.1 |
