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6SGI

Nek2 kinase bound to inhibitor 96

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASerine/threonine-protein kinase Nek2polymer27932662.51UniProt (P51955)
Pfam (PF00069)
In PDB
Homo sapiens (Human)HSPK 21,Never in mitosis A-related kinase 2,NimA-related protein kinase 2,NimA-like protein kinase 1
2A4-[(6-ethyl-7~{H}-purin-2-yl)amino]benzenesulfonamidenon-polymer318.41Chemie (LCB)
3ACHLORIDE IONnon-polymer35.53Chemie (CL)
4waterwater18.0134Chemie (HOH)
Sequence modifications
A: 1 - 271 (UniProt: P51955)
PDBExternal DatabaseDetails
Leu 272-expression tag
Glu 273-expression tag
His 274-expression tag
His 275-expression tag
His 276-expression tag
His 277-expression tag
His 278-expression tag
His 279-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32662.5
Non-Polymers*Number of molecules4
Total formula weight424.7
All*Total formula weight33087.2
*Water molecules are not included.

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PDB entries from 2024-05-29

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