6SGI
Nek2 kinase bound to inhibitor 96
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Nek2 | polymer | 279 | 32662.5 | 1 | UniProt (P51955) Pfam (PF00069) | Homo sapiens (Human) | HSPK 21,Never in mitosis A-related kinase 2,NimA-related protein kinase 2,NimA-like protein kinase 1 |
| 2 | B (A) | 4-[(6-ethyl-7~{H}-purin-2-yl)amino]benzenesulfonamide | non-polymer | 318.4 | 1 | Chemie (LCB) | |||
| 3 | C, D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | F (A) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A: 1 - 271 (UniProt: P51955)
| PDB | External Database | Details |
|---|---|---|
| Leu 272 | - | expression tag |
| Glu 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
| His 277 | - | expression tag |
| His 278 | - | expression tag |
| His 279 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32662.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 424.7 | |
| All* | Total formula weight | 33087.2 |
