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6SFU

Human Carbonic Anhydrase II in complex with a furan-containing benzenesulfonamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer26529806.61UniProt (P00918)
Pfam (PF00194)
Homo sapiens (Human)Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
MERCURY (II) IONnon-polymer200.61Chemie (HG)
4D
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
5E, F
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
6G
(A)
(4-CARBOXYPHENYL)(CHLORO)MERCURYnon-polymer357.21Chemie (BE7)
7H, I
(A)
4-(furan-2-ylmethylamino)benzenesulfonamidenon-polymer252.32Chemie (LBQ)
8J
(A)
waterwater18.0231Chemie (HOH)
Sequence modifications
A: 1 - 261 (UniProt: P00918)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ser -3-expression tag
Pro -2-expression tag
Glu -1-expression tag
Phe 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29806.6
Non-Polymers*Number of molecules8
Total formula weight1251.8
All*Total formula weight31058.4
*Water molecules are not included.

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PDB entries from 2025-07-23

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