6SE6
Class2 : CENP-A nucleosome in complex with CENP-C central region
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | Histone H3-like centromeric protein A | polymer | 140 | 16023.6 | 2 | UniProt (P49450) Pfam (PF00125) In PDB | Homo sapiens (Human) | Centromere autoantigen A,Centromere protein A,CENP-A |
2 | B, F | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (Human) | |
3 | C, G | Histone H2A type 2-A | polymer | 130 | 14125.5 | 2 | UniProt (Q6FI13) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (Human) | Histone H2A.2,Histone H2A/o |
4 | D, H | Histone H2B type 1-C/E/F/G/I | polymer | 126 | 13937.2 | 2 | UniProt (P62807) Pfam (PF00125) In PDB | Homo sapiens (Human) | Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l |
5 | I | DNA (145-MER) | polymer | 145 | 44520.4 | 1 | synthetic construct | ||
6 | J | DNA (145-MER) | polymer | 145 | 44991.7 | 1 | synthetic construct | ||
7 | V | Centromere protein C | polymer | 124 | 14204.8 | 1 | UniProt (Q03188) Pfam (PF15620) In PDB | Homo sapiens (Human) | CENP-C,Centromere autoantigen C,Centromere protein C 1,CENP-C 1,Interphase centromere complex protein 7 |
Sequence modifications
V: 426 - 537 (UniProt: Q03188)
PDB | External Database | Details |
---|---|---|
Gly 414 | - | expression tag |
Pro 415 | - | expression tag |
Leu 416 | - | expression tag |
Gly 417 | - | expression tag |
Ser 418 | - | expression tag |
Pro 419 | - | expression tag |
Glu 420 | - | expression tag |
Phe 421 | - | expression tag |
Gly 422 | - | expression tag |
Arg 423 | - | expression tag |
Ala 424 | - | expression tag |
Thr 425 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 11 |
Total formula weight | 214678.4 | |
All* | Total formula weight | 214678.4 |