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6SDE

Crystal structure of wild-type cMET bound by savolitinib

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hepatocyte growth factor receptorpolymer30934842.31UniProt (P08581)
Pfam (PF07714)
Homo sapiens (Human)HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met
2B
(A)
volitinibnon-polymer345.41Chemie (V0L)
3C
(A)
waterwater18.056Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34842.3
Non-Polymers*Number of molecules1
Total formula weight345.4
All*Total formula weight35187.7
*Water molecules are not included.

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PDB entries from 2025-07-16

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