6SD9

Crystal structure of wild-type cMET bound by foretinib

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Hepatocyte growth factor receptor	polymer	309	34842.3	1	UniProt (P08581) Pfam (PF07714) In PDB	Homo sapiens (Human)	HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met
2	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
3	A	N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide	non-polymer		632.7	1	Chemie (88Z)
4		water	water		18.0	55	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34842.3
Non-Polymers*	Number of molecules	2
	Total formula weight	668.1
All*	Total formula weight	35510.4

*Water molecules are not included.