6SBO
Estrogen receptor mutant L536S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estrogen receptor | polymer | 260 | 29608.9 | 2 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (Human) | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 2 | C, D (A, B) | 6-(2,4-dichlorophenyl)-5-[4-[(3~{S})-1-(3-fluoranylpropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7~{H}-benzo[7]annulene-2-carboxylic acid | non-polymer | 554.5 | 2 | Chemie (L5B) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 350 | Chemie (HOH) |
Sequence modifications
A, B: 297 - 554 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Gly 295 | - | expression tag |
| Ala 296 | - | expression tag |
| Ser 536 | Leu 363 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59217.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1109.0 | |
| All* | Total formula weight | 60326.7 |
