6S8I

Structure of ZEBOV GP in complex with 3T0265 antibody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L, O, U	Light Chain	polymer	218	23080.5	3		Homo sapiens
2	H, P, Y	Heavy Chain	polymer	224	23785.7	3		Homo sapiens
3	A, C, E	Enveloped Glycoprotein 1	polymer	323	35707.0	3	Pfam (PF01611) UniProt (by SIFTS) (Q05320) In PDB	Ebola virus
4	B, D, F	Envelope glycoprotein	polymer	168	18989.4	3	UniProt (A0A0U3BWW0) UniProt (by SIFTS) (Q05320) In PDB	Ebola virus
5	G, I, J	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)

Sequence modifications

B, D, F: 502 - 632 (UniProt: A0A0U3BWW0)

PDB	External Database	Details
Gly 633	-	expression tag
Ser 634	-	expression tag
Gly 635	-	expression tag
Tyr 636	-	expression tag
Ile 637	-	expression tag
Pro 638	-	expression tag
Glu 639	-	expression tag
Ala 640	-	expression tag
Pro 641	-	expression tag
Arg 642	-	expression tag
Asp 643	-	expression tag
Gly 644	-	expression tag
Gln 645	-	expression tag
Ala 646	-	expression tag
Tyr 647	-	expression tag
Val 648	-	expression tag
Arg 649	-	expression tag
Lys 650	-	expression tag
Asp 651	-	expression tag
Gly 652	-	expression tag
Glu 653	-	expression tag
Trp 654	-	expression tag
Val 655	-	expression tag
Leu 656	-	expression tag
Leu 657	-	expression tag
Ser 658	-	expression tag
Thr 659	-	expression tag
Phe 660	-	expression tag
Leu 661	-	expression tag
Gly 662	-	expression tag
Thr 663	-	expression tag
His 664	-	expression tag
His 665	-	expression tag
His 666	-	expression tag
His 667	-	expression tag
His 668	-	expression tag
His 669	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	304687.8
Branched	Number of molecules	3
	Total formula weight	1273.2
All*	Total formula weight	305961.0

*Water molecules are not included.