6S8D
Structure of ZEBOV GP in complex with 1T0227 antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G, H (L, O, U) | Light chain | polymer | 218 | 23138.5 | 3 | Homo sapiens | ||
| 2 | B, K, L (H, P, Y) | Heavy chain | polymer | 231 | 24747.7 | 3 | Homo sapiens | ||
| 3 | C, I, J (A, C, E) | Envelope glycoprotein | polymer | 323 | 35707.0 | 3 | UniProt (A0A0U3BWW0) Pfam (PF01611) UniProt (by SIFTS) (Q05320) | Ebola virus | |
| 4 | D, E, F (B, D, F) | Envelope glycoprotein | polymer | 168 | 18989.4 | 3 | UniProt (A0A0U3BWW0) Pfam (PF22307) UniProt (by SIFTS) (Q05320) | Ebola virus | |
| 5 | M, N, O (G, I, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
A, C, E: 32 - 334 (UniProt: A0A0U3BWW0)
B, D, F: 502 - 632 (UniProt: A0A0U3BWW0)
| PDB | External Database | Details |
|---|---|---|
| Glu 28 | - | expression tag |
| Thr 29 | - | expression tag |
| Gly 30 | - | expression tag |
| Arg 31 | - | expression tag |
| Ala 42 | Thr 42 | conflict |
| Val 310 | Ala 310 | conflict |
| Thr 313 | Asn 313 | conflict |
| His 314 | Arg 314 | conflict |
| His 315 | Ala 315 | conflict |
| Gln 316 | Lys 316 | conflict |
| Asp 317 | Asn 317 | conflict |
| Thr 318 | Ile 318 | conflict |
| Gly 319 | Ser 319 | conflict |
| Glu 320 | Gly 320 | conflict |
| Glu 321 | Gln 321 | conflict |
| Ala 323 | Pro 323 | conflict |
| Ser 324 | Ala 324 | conflict |
| Ser 325 | Arg 325 | conflict |
| Gly 326 | Thr 326 | conflict |
| Lys 327 | Ser 327 | conflict |
| Leu 328 | Ser 328 | conflict |
| Gly 329 | Asp 329 | conflict |
| Leu 330 | Pro 330 | conflict |
| Ile 331 | Gly 331 | conflict |
| Ile 335 | - | expression tag |
| Ala 336 | - | expression tag |
| Gly 337 | - | expression tag |
| Val 338 | - | expression tag |
| Ala 339 | - | expression tag |
| Gly 340 | - | expression tag |
| Leu 341 | - | expression tag |
| Ile 342 | - | expression tag |
| Thr 343 | - | expression tag |
| Gly 344 | - | expression tag |
| Gly 345 | - | expression tag |
| Arg 346 | - | expression tag |
| Arg 347 | - | expression tag |
| Thr 348 | - | expression tag |
| Arg 349 | - | expression tag |
| Arg 350 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 633 | - | expression tag |
| Ser 634 | - | expression tag |
| Gly 635 | - | expression tag |
| Tyr 636 | - | expression tag |
| Ile 637 | - | expression tag |
| Pro 638 | - | expression tag |
| Glu 639 | - | expression tag |
| Ala 640 | - | expression tag |
| Pro 641 | - | expression tag |
| Arg 642 | - | expression tag |
| Asp 643 | - | expression tag |
| Gly 644 | - | expression tag |
| Gln 645 | - | expression tag |
| Ala 646 | - | expression tag |
| Tyr 647 | - | expression tag |
| Val 648 | - | expression tag |
| Arg 649 | - | expression tag |
| Lys 650 | - | expression tag |
| Asp 651 | - | expression tag |
| Gly 652 | - | expression tag |
| Glu 653 | - | expression tag |
| Trp 654 | - | expression tag |
| Val 655 | - | expression tag |
| Leu 656 | - | expression tag |
| Leu 657 | - | expression tag |
| Ser 658 | - | expression tag |
| Thr 659 | - | expression tag |
| Phe 660 | - | expression tag |
| Leu 661 | - | expression tag |
| Gly 662 | - | expression tag |
| Thr 663 | - | expression tag |
| His 664 | - | expression tag |
| His 665 | - | expression tag |
| His 666 | - | expression tag |
| His 667 | - | expression tag |
| His 668 | - | expression tag |
| His 669 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 307747.9 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| All* | Total formula weight | 309021.1 |
