6S88
Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator N-(2-Methoxy-5-((1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)sulfonyl)phenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fumarate hydratase class II | polymer | 474 | 50191.8 | 4 | UniProt (A0A045IXZ8) Pfam (PF00206) Pfam (PF10415) UniProt (by SIFTS) (P9WN93) | Mycobacterium tuberculosis | Fumarase C,Aerobic fumarase,Iron-independent fumarase |
| 2 | E, H (A, C) | ~{N}-[2-methoxy-5-(1,2,4,5-tetrahydro-3-benzazepin-3-ylsulfonyl)phenyl]-2-(4-oxidanylidene-3~{H}-phthalazin-1-yl)ethanamide | non-polymer | 518.6 | 2 | Chemie (L0K) | |||
| 3 | F (B) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | G (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 1312 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 200767.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1107.5 | |
| All* | Total formula weight | 201874.7 |
