6S85

Cutting state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and dsDNA.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (C, D)	Nuclease SbcCD subunit C	polymer	1048	118851.5	2	UniProt (A0A037YDI0) Pfam (PF13476) Pfam (PF13558) UniProt (by SIFTS) (P13458)	Escherichia coli
2	C, D (A, B)	Nuclease SbcCD subunit D	polymer	407	45599.2	2	UniProt (C3TMC7) Pfam (PF00149) Pfam (PF12320) UniProt (by SIFTS) (P0AG76)	Escherichia coli
3	E (E)	DNA (31-MER)	polymer	60	18518.9	1		synthetic construct
4	F (F)	DNA (32-MER)	polymer	60	18464.8	1		synthetic construct
5	G, I (C, D)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
6	H, J (C, D)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7	K, L, M, N (A, B)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)

Sequence modifications

A, B: 1 - 400 (UniProt: C3TMC7)

PDB	External Database	Details
Ser 84	His 84	conflict
Gly 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	365885.2
Non-Polymers*	Number of molecules	8
	Total formula weight	1122.8
All*	Total formula weight	367007.9

*Water molecules are not included.