6S6R
First crystal structure of parasitic PEX14 in complex with a fragment molecule 1H-indole-7-carboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxin 14 | polymer | 69 | 7883.1 | 1 | UniProt (Q8IEW2) | Trypanosoma brucei brucei | |
| 2 | B, C, D (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E (A) | 1~{H}-indole-7-carboxylic acid | non-polymer | 161.2 | 1 | Chemie (KXQ) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | H (A) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A: 1 - 66 (UniProt: Q8IEW2)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Met 0 | - | expression tag |
| Trp 1 | Glu 19 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 7883.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 619.6 | |
| All* | Total formula weight | 8502.6 |
