6S6R
First crystal structure of parasitic PEX14 in complex with a fragment molecule 1H-indole-7-carboxylic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peroxin 14 | polymer | 69 | 7883.1 | 1 | UniProt (Q8IEW2) Pfam (PF04695) In PDB | Trypanosoma brucei brucei | |
2 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
3 | A | 1~{H}-indole-7-carboxylic acid | non-polymer | 161.2 | 1 | Chemie (KXQ) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
6 | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A: 1 - 66 (UniProt: Q8IEW2)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ala -1 | - | expression tag |
Met 0 | - | expression tag |
Trp 1 | Glu 19 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 7883.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 619.6 | |
All* | Total formula weight | 8502.6 |