6S4I
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Insulin | polymer | 21 | 2349.6 | 1 | UniProt (P01308) | Homo sapiens (Human) | |
| 2 | B (B) | Insulin | polymer | 29 | 3323.8 | 1 | UniProt (P01308) Pfam (PF00049) | Homo sapiens (Human) | |
| 3 | C, D (B) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 1 - 21 (UniProt: P01308)
B: 1 - 29 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Glu 14 | Tyr 103 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| His 25 | Phe 49 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 5673.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 124.0 | |
| All* | Total formula weight | 5797.5 |
