6S26
Crystal structure of human wild type STING in complex with 2'-3'-cyclic-GMP-7-deaza-AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon protein | polymer | 204 | 23189.1 | 2 | UniProt (A0A2R3XZB7) Pfam (PF15009) UniProt (by SIFTS) (Q86WV6) | Homo sapiens (Human) | |
| 2 | C (B) | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one | non-polymer | 673.4 | 1 | Chemie (KT2) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46378.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 673.4 | |
| All* | Total formula weight | 47051.6 |
