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6S26

Crystal structure of human wild type STING in complex with 2'-3'-cyclic-GMP-7-deaza-AMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BStimulator of interferon proteinpolymer20423189.12UniProt (A0A2R3XZB7)
Pfam (PF15009)
UniProt (by SIFTS) (Q86WV6)
In PDB
Homo sapiens (Human)
2B2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-onenon-polymer673.41Chemie (KT2)
3waterwater18.0162Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight46378.1
Non-Polymers*Number of molecules1
Total formula weight673.4
All*Total formula weight47051.6
*Water molecules are not included.

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PDB entries from 2024-06-12

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