6S1Y

Crystal structure of Anopheles gambiae AnoACE2 in complex with gamma-Polyglutamic Acid.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Angiotensin-converting enzyme	polymer	621	72041.2	1	UniProt (A0NFU8)	Anopheles gambiae (African malaria mosquito)
2	B (B)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
3	C (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	D (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG) PubChem (8117)
5	E, F (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	G (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
7	H (A)	(2~{S})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]pentanedioic acid	non-polymer		276.2	1	Chemie (KSN) PubChem (453622) PubChem (11369406) PubChem (92865) PubChem (87289628) PubChem (7018228) PubChem (88051949) PubChem (558343)
8	I (A)	water	water		18.0	198	Chemie (HOH)

Sequence modifications

A: 27 - 638 (UniProt: A0NFU8)

PDB	External Database	Details
Lys 639	-	expression tag
His 640	-	expression tag
His 641	-	expression tag
His 642	-	expression tag
His 643	-	expression tag
His 644	-	expression tag
His 645	-	expression tag
His 646	-	expression tag
His 647	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	72041.2
Branched	Number of molecules	2
	Total formula weight	1010.9
Non-Polymers*	Number of molecules	5
	Total formula weight	571.9
All*	Total formula weight	73624.1

*Water molecules are not included.