6S0A

Crystal Structure of Properdin (TSR domains N12 & 456)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Properdin	polymer	225	25058.5	1	UniProt (P27918) Pfam (PF00090) Pfam (PF22195)	Homo sapiens (Human)	Complement factor P
2	B (B)	Properdin	polymer	166	17986.2	1	UniProt (P27918) Pfam (PF18487) Pfam (PF00090)	Homo sapiens (Human)	Complement factor P
3	C, E (C, E)	beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose	branched		326.3	2	In PDB GlyTouCan (G36855WW)
4	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	F, G, H, I, J... (A, B)	alpha-D-mannopyranose	non-polymer		180.2	10	Chemie (MAN)
6	P (B)	alpha-L-fucopyranose	non-polymer		164.2	1	Chemie (FUC)
7	Q, R (A, B)	water	water		18.0	11	Chemie (HOH)

Sequence modifications

A: 256 - 469 (UniProt: P27918)

PDB	External Database	Details
Gly 254	-	expression tag
Ser 255	-	expression tag
Ala 470	-	expression tag
Ala 471	-	expression tag
Ala 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag
His 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43044.7
Branched	Number of molecules	3
	Total formula weight	1077.0
Non-Polymers*	Number of molecules	11
	Total formula weight	1965.7
All*	Total formula weight	46087.4

*Water molecules are not included.