6RYU

Nucleosome-CHD4 complex structure (two CHD4 copies)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.2	polymer	136	15435.1	2	UniProt (P84233) Pfam (PF00125)	Xenopus laevis (African clawed frog)
2	B, F (B, F)	Histone H4	polymer	103	11394.4	2	UniProt (P62799) Pfam (PF15511)	Xenopus laevis (African clawed frog)
3	C, G (C, G)	Histone H2A type 1	polymer	130	14109.4	2	UniProt (P06897) Pfam (PF00125) Pfam (PF16211)	Xenopus laevis (African clawed frog)
4	D, H (D, H)	Histone H2B 1.1	polymer	123	13655.9	2	UniProt (P02281) Pfam (PF00125)	Xenopus laevis (African clawed frog)	H2B1.1
5	I (I)	DNA (149-MER)	polymer	149	45781.2	1		synthetic construct
6	J (J)	DNA (149-MER)	polymer	149	46203.4	1		synthetic construct
7	K, L (W, V)	Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4	polymer	1927	219628.0	2	UniProt (Q14839) Pfam (PF00176) Pfam (PF00271) Pfam (PF06465) Pfam (PF06461) Pfam (PF08074) Pfam (PF08073) Pfam (PF00628) Pfam (PF00385)	Homo sapiens (Human)	CHD-4,ATP-dependent helicase CHD4,Mi-2 autoantigen 218 kDa protein,Mi2-beta,CHD-4,ATP-dependent helicase CHD4,Mi-2 autoantigen 218 kDa protein,Mi2-beta
8	M, Q (W, V)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
9	N, R (W, V)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
10	O, P, S, T (W, V)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)

Sequence modifications

A, E: 0 - 135 (UniProt: P84233)

PDB	External Database	Details
Ala 102	Gly 103	conflict

C, G: 0 - 129 (UniProt: P06897)

PDB	External Database	Details
Arg 99	Gly 100	conflict
Ser 123	Ala 124	conflict

D, H: 1 - 122 (UniProt: P02281)

PDB	External Database	Details
Met 0	-	initiating methionine
Thr 29	Ser 33	conflict

W, V: 1 - 1200 (UniProt: Q14839)

W, V: 1405 - 1416 (PDB: 6RYU)
W, V: 1417 - 2128 (UniProt: Q14839)

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.