6RYR
Nucleosome-CHD4 complex structure (single CHD4 copy)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.2 | polymer | 136 | 15435.1 | 2 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 2 | B, F (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 3 | C, G (C, G) | Histone H2A type 1 | polymer | 130 | 14109.4 | 2 | UniProt (P06897) Pfam (PF00125) Pfam (PF16211) | Xenopus laevis (African clawed frog) | |
| 4 | D, H (D, H) | Histone H2B 1.1 | polymer | 123 | 13655.9 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 5 | I (I) | DNA (149-MER) | polymer | 149 | 45781.2 | 1 | synthetic construct | ||
| 6 | J (J) | DNA (149-MER) | polymer | 149 | 46203.4 | 1 | synthetic construct | ||
| 7 | K (W) | Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4 | polymer | 1927 | 219628.0 | 1 | UniProt (Q14839) Pfam (PF00176) Pfam (PF00271) Pfam (PF06465) Pfam (PF06461) Pfam (PF08074) Pfam (PF08073) Pfam (PF00628) Pfam (PF00385) | Homo sapiens (Human) | CHD-4,ATP-dependent helicase CHD4,Mi-2 autoantigen 218 kDa protein,Mi2-beta,CHD-4,ATP-dependent helicase CHD4,Mi-2 autoantigen 218 kDa protein,Mi2-beta,CHD-4,ATP-dependent helicase CHD4,Mi-2 autoantigen 218 kDa protein,Mi2-beta |
| 8 | L (W) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 9 | M (W) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 10 | N, O (W) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, E: 0 - 135 (UniProt: P84233)
C, G: 0 - 129 (UniProt: P06897)
D, H: 1 - 122 (UniProt: P02281)
W: 1 - 1200 (UniProt: Q14839)
W: 1201 - 1212 (PDB: 6RYR)
W: 1213 - 1924 (UniProt: Q14839)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Gly 103 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 99 | Gly 100 | conflict |
| Ser 123 | Ala 124 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Thr 29 | Ser 33 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
W: 1213 - 1924 (UniProt: Q14839)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 420802.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 661.3 | |
| All* | Total formula weight | 421463.8 |
