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6RVX

Inward-open structure of the ASCT2 (SLC1A5) mutant C467R in presence of TBOA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Neutral amino acid transporter B(0)polymer54757521.83UniProt (Q15758)
Pfam (PF00375)
Homo sapiens (Human)ATB(0),Baboon M7 virus receptor,RD114/simian type D retrovirus receptor,Sodium-dependent neutral amino acid transporter type 2,Solute carrier family 1 member 5
Sequence modifications
A, B, C: 1 - 541 (UniProt: Q15758)
PDBExternal DatabaseDetails
Arg 467Cys 467engineered mutation
His 542-expression tag
His 543-expression tag
His 544-expression tag
His 545-expression tag
His 546-expression tag
His 547-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight172565.5
All*Total formula weight172565.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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