6RVC
Crystal structure of Patched-1 ectodomain 2 (PTCH1-ECD2) in complex with nanobody 75
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Protein patched homolog 1 | polymer | 261 | 30659.3 | 3 | UniProt (Q13635) Pfam (PF02460) | Homo sapiens (Human) | PTC1 |
| 2 | D, E, F (D, E, F) | Nanobody NB75 | polymer | 134 | 14820.2 | 3 | Lama glama | ||
| 3 | G, H (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | I (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | J, K, L, M, N... (A, B, C, D, E...) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A, B, C: 772 - 1023 (UniProt: Q13635)
| PDB | External Database | Details |
|---|---|---|
| Glu 763 | - | expression tag |
| Thr 764 | - | expression tag |
| Gly 765 | - | expression tag |
| His 766 | - | expression tag |
| His 767 | - | expression tag |
| His 768 | - | expression tag |
| His 769 | - | expression tag |
| His 770 | - | expression tag |
| His 771 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 136438.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 538.5 | |
| All* | Total formula weight | 136976.9 |
