6RV6

Structure of properdin lacking TSR3 based on anomalous data

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Properdin	polymer	170	18636.9	1	UniProt (P27918) Pfam (PF18487) Pfam (PF00090) In PDB	Homo sapiens (Human)	Complement factor P
2	B	Properdin	polymer	221	24724.1	1	UniProt (P27918) Pfam (PF00090) Pfam (PF22195) In PDB	Homo sapiens (Human)	Complement factor P
3	C, D, E	beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose	branched		326.3	3	In PDB GlyTouCan (G36855WW)
4	F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
5	A, B	alpha-D-mannopyranose	non-polymer		180.2	12	Chemie (MAN)

Sequence modifications

A: 28 - 191 (UniProt: P27918)

PDB	External Database	Details
Glu 192	-	expression tag
Asn 193	-	expression tag
Leu 194	-	expression tag
Tyr 195	-	expression tag
Phe 196	-	expression tag
Gln 197	-	expression tag

B: 256 - 469 (UniProt: P27918)

PDB	External Database	Details
Gly 255	-	expression tag
Glu 470	-	expression tag
Asn 471	-	expression tag
Leu 472	-	expression tag
Tyr 473	-	expression tag
Phe 474	-	expression tag
Gln 475	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43361.1
Branched	Number of molecules	4
	Total formula weight	1549.4
Non-Polymers*	Number of molecules	12
	Total formula weight	2161.9
All*	Total formula weight	47072.4

*Water molecules are not included.